| Long name: |
FITC Conjugated, SGSH/Sulphamidase Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SGSH/Sulphamidase |
| Specificity: |
This is a highly specific antibody against SGSH/Sulphamidase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
310-360/502 |
| Subcellular location: |
Lysosome |
| Source: |
KLH conjugated synthetic peptide derived from human Sulphamidase |
| Gene ID number: |
6448 |
| Swiss Prot: |
P51688 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in the gene encoding sulfamidase are the cause of Sanfilippo syndrome A, Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids, It has been suggested that sulfamidase may be involved in the lysosomal degradation of heparan sulfate, MPS3A or SGSH, SFMD, Sanfilippo syndrome A is characterized by severe central nervous system degeneration but relatively mild somatic manifestations, Sulfamidase, also known as HSS, an autosomal recessive lysosomal storage disease caused by impaired degradation of heparan sulfate, is a 502 amino acid lysosome that belongs to the sulfatase family, Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
HSS MPS3A SFMD |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SGSH/Sulphamidase Conjugated |
| Short name: |
FITC Conjugated, SGSH/Sulphamidase Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SGSH/Sulphamidase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10818 |
| Gene: |
SGSH |
More about : SGSH |
| Long gene name: |
N-sulfoglucosamine sulfohydrolase |
| Synonyms name: |
sulfamidase mucopolysaccharidosis type IIIA |
| Locus: |
17q25, 3 |
| Discovery year: |
1997-06-24 |
| GenBank acession: |
BC047318 |
| Entrez gene record: |
6448 |
| Pubmed identfication: |
7493035 |
| RefSeq identity: |
NM_000199 |
| Classification: |
Sulfatases |
| Havana BLAST/BLAT: |
OTTHUMG00000177569 |