| Long name: |
HRP Conjugated, SGSH/Sulphamidase Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SGSH/Sulphamidase |
| Specificity: |
This is a highly specific antibody against SGSH/Sulphamidase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
310-360/502 |
| Subcellular location: |
Lysosome |
| Source: |
KLH conjugated synthetic peptide derived from human Sulphamidase |
| Gene ID number: |
6448 |
| Swiss Prot: |
P51688 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in the gene encoding sulfamidase are the cause of Sanfilippo syndrome A, Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids, It has been suggested that sulfamidase may be involved in the lysosomal degradation of heparan sulfate, MPS3A or SGSH, SFMD, Sanfilippo syndrome A is characterized by severe central nervous system degeneration but relatively mild somatic manifestations, Sulfamidase, also known as HSS, an autosomal recessive lysosomal storage disease caused by impaired degradation of heparan sulfate, is a 502 amino acid lysosome that belongs to the sulfatase family, Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
HSS MPS3A SFMD |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
SGSH/Sulphamidase Conjugated |
| Short name: |
Conjugated, SGSH/Sulphamidase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, SGSH/Sulphamidase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10818 |
| Gene: |
SGSH |
More about : SGSH |
| Long gene name: |
N-sulfoglucosamine sulfohydrolase |
| Synonyms name: |
sulfamidase mucopolysaccharidosis type IIIA |
| Locus: |
17q25, 3 |
| Discovery year: |
1997-06-24 |
| GenBank acession: |
BC047318 |
| Entrez gene record: |
6448 |
| Pubmed identfication: |
7493035 |
| RefSeq identity: |
NM_000199 |
| Classification: |
Sulfatases |
| Havana BLAST/BLAT: |
OTTHUMG00000177569 |