| Long name: |
ALEXA FLUOR 594 Conjugated, SGSH/Sulphamidase Polyclonal Antibody |
| Also known as: |
Anti-SGSH/Sulphamidase PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SGSH/Sulphamidase |
| Specificity: |
This is a highly specific antibody against SGSH/Sulphamidase |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
310-360/502 |
| Subcellular location: |
Lysosome |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sulphamidase |
| Gene ID Number: |
6448 |
| Swiss Prot: |
P51688 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Defects in the gene encoding sulfamidase are the cause of Sanfilippo syndrome A, Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids, It has been suggested that sulfamidase may be involved in the lysosomal degradation of heparan sulfate, MPS3A or SGSH, SFMD, Sanfilippo syndrome A is characterized by severe central nervous system degeneration but relatively mild somatic manifestations, Sulfamidase, also known as HSS, an autosomal recessive lysosomal storage disease caused by impaired degradation of heparan sulfate, is a 502 amino acid lysosome that belongs to the sulfatase family, Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HSS MPS3A SFMD |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
SGSH/Sulphamidase |
| Short name: |
SGSH/Sulphamidase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, SGSH/Sulphamidase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10818 |
| Gene: |
SGSH |
More about : SGSH |
| Long gene name: |
N-sulfoglucosamine sulfohydrolase |
| Synonyms name: |
sulfamidase mucopolysaccharidosis type IIIA |
| Locus: |
17q25, 3 |
| Discovery year: |
1997-06-24 |
| GenBank acession: |
BC047318 |
| Entrez gene record: |
6448 |
| Pubmed identfication: |
7493035 |
| RefSeq identity: |
NM_000199 |
| Classification: |
Sulfatases |
| Havana BLAST/BLAT: |
OTTHUMG00000177569 |