| Catalog number: | F51969-0.4ML |
|---|---|
| Price: | 688 € |
| Supplier: | acr |
| Product name: | AIM2 Antibody |
| Quantity: | 0,2 ml |
| Other quantities: | 0.08 ml 199€ 0.1mg 406€ 0.1ml 263€ 1 vial 521€ |
| Related search: |
| Category: | Antibody |
|---|---|
| Concentration: | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | AIM2 |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | ELISA, FACS, IF, WB |
| Recommended dilutions: | Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes: | Titration of the AIM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: | This AIM2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: | O14862 |
| Purity: | Antigen affinity |
| Description: | Can also trigger PYCARD-dependent, Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner, Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity, Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18, [UniProt], caspase-1-independent cell death that involves caspase-8 (By similarity), Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages |
| Immunogen: | A portion of amino acids 1-50 from the human protein was used as the immunogen for this AIM2 antibody |
| Storage: | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the AIM2 antibody and store frozen at -20 deg |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | AIM2 |
| Short name: | AIM2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | AIM2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 357 |
| Gene: | AIM2 | More about : AIM2 |
| Long gene name: | absent in melanoma 2 |
| Synonyms: | PYHIN4 |
| Locus: | 1q23, 1-q23, 2 |
| Discovery year: | 1999-04-22 |
| GenBank acession: | AF024714 |
| Entrez gene record: | 9447 |
| Pubmed identfication: | 9242382 |
| RefSeq identity: | NM_004833 |
| Classification: | Pyrin and HIN domain family |
| Havana BLAST/BLAT: | OTTHUMG00000037183 |
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