| Long name: |
Biotin Conjugated, AIM2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AIM2 |
| Specificity: |
This is a highly specific antibody against AIM2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
250-300/354 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse AIM2 |
| Gene ID number: |
383619 |
| Swiss Prot: |
Q91VJ1 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Can also trigger PYCARD-dependent, Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner, Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18, caspase-1-independent cell death that involves caspase-8, Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PYHIN4 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AIM2 Conjugated |
| Short name: |
Conjugated, AIM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, AIM2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
357 |
| Gene: |
AIM2 |
More about : AIM2 |
| Long gene name: |
absent in melanoma 2 |
| Locus: |
1q23, 1-q23, 2 |
| Discovery year: |
1999-04-22 |
| GenBank acession: |
AF024714 |
| Entrez gene record: |
9447 |
| Pubmed identfication: |
9242382 |
| RefSeq identity: |
NM_004833 |
| Classification: |
Pyrin and HIN domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000037183 |