| Long name: |
Cy7 Conjugated, AIM2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AIM2 |
| Specificity: |
This is a highly specific antibody against AIM2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
250-300/354 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse AIM2 |
| Gene ID number: |
383619 |
| Swiss Prot: |
Q91VJ1 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Can also trigger PYCARD-dependent, Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner, Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18, caspase-1-independent cell death that involves caspase-8, Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
PYHIN4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
AIM2 Conjugated |
| Short name: |
Conjugated, AIM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, AIM2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
357 |
| Gene: |
AIM2 |
More about : AIM2 |
| Long gene name: |
absent in melanoma 2 |
| Locus: |
1q23, 1-q23, 2 |
| Discovery year: |
1999-04-22 |
| GenBank acession: |
AF024714 |
| Entrez gene record: |
9447 |
| Pubmed identfication: |
9242382 |
| RefSeq identity: |
NM_004833 |
| Classification: |
Pyrin and HIN domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000037183 |