| Long name: |
ALEXA FLUOR 647 Conjugated, AIM2 Polyclonal Antibody |
| Also known as: |
Anti-AIM2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AIM2 |
| Specificity: |
This is a highly specific antibody against AIM2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
250-300/354 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse AIM2 |
| Gene ID Number: |
383619 |
| Swiss Prot: |
Q91VJ1 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Can also trigger PYCARD-dependent, Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner, Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18, caspase-1-independent cell death that involves caspase-8, Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PYHIN4 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the AIM2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
AIM2 |
| Short name: |
AIM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, AIM2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
357 |
| Gene: |
AIM2 |
More about : AIM2 |
| Long gene name: |
absent in melanoma 2 |
| Locus: |
1q23, 1-q23, 2 |
| Discovery year: |
1999-04-22 |
| GenBank acession: |
AF024714 |
| Entrez gene record: |
9447 |
| Pubmed identfication: |
9242382 |
| RefSeq identity: |
NM_004833 |
| Classification: |
Pyrin and HIN domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000037183 |