| Catalog number: | F47779-0.08ML |
|---|---|
| Price: | 2105 € |
| Supplier: | MBS Recombinant Proteins |
| Product name: | Txnip Antibody |
| Quantity: | 100ug |
| Other quantities: | 0.025mg 176€ 0.08 ml 199€ 0.1mg 320€ 0.1ml 263€ 0.4 ml 406€ 1 vial 521€ 100ug 431€ |
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| Category: | Antibody |
|---|---|
| Concentration: | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | Txnip |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: | ELISA, WB |
| Recommended dilutions: | Western blot: 1:1000 |
| Notes: | Titration of the Txnip antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: | This Txnip antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: | Q8BG60 |
| Purity: | Antigen affinity |
| Description: | Functions as a transcriptional repressor, Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, Required for the maturation of natural killer cells, [UniProt], and over-expression will induce G0/G1 cell cycle arrest, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability |
| Immunogen: | A portion of amino acids 116-145 from the mouse protein was used as the immunogen for this Txnip antibody |
| Storage: | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Txnip antibody and store frozen at -20 deg |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | Txnip |
| Short name: | Txnip Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | Txnip (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 16952 |
| Gene: | TXNIP | More about : TXNIP |
| Long gene name: | thioredoxin interacting protein |
| Synonyms: | VDUP1 EST01027 HHCPA78 THIF ARRDC6 |
| Synonyms name: | upregulated by 1, 25-dihydroxyvitamin D-3 thioredoxin binding protein 2 |
| Locus: | 1q21, 1 |
| Discovery year: | 2001-12-12 |
| GenBank acession: | S73591 |
| Entrez gene record: | 10628 |
| Pubmed identfication: | 8086474 |
| RefSeq identity: | NM_006472 |
| Classification: | Alpha arrestins |
| Havana BLAST/BLAT: | OTTHUMG00000013755 |
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