| Long name: |
FITC Conjugated, TXNIP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TXNIP |
| Specificity: |
This is a highly specific antibody against TXNIP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
140-190/391 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human TXNIP |
| Gene ID number: |
10628 |
| Swiss Prot: |
Q9H3M7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a suppressor of tumor cell growth, Functions as a transcriptional repressor, Inhibits the proteasomal degradation of DDIT4, Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, Required for the maturation of natural killer cells, and over-expression will induce G0/G1 cell cycle arrest, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1), blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
VDUP1 EST01027 HHCPA78 THIF ARRDC6 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TXNIP Conjugated |
| Short name: |
FITC Conjugated, TXNIP Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TXNIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16952 |
| Gene: |
TXNIP |
More about : TXNIP |
| Long gene name: |
thioredoxin interacting protein |
| Synonyms name: |
upregulated by 1, 25-dihydroxyvitamin D-3 thioredoxin binding protein 2 |
| Locus: |
1q21, 1 |
| Discovery year: |
2001-12-12 |
| GenBank acession: |
S73591 |
| Entrez gene record: |
10628 |
| Pubmed identfication: |
8086474 |
| RefSeq identity: |
NM_006472 |
| Classification: |
Alpha arrestins |
| Havana BLAST/BLAT: |
OTTHUMG00000013755 |