| Long name: |
Cy7 Conjugated, TXNIP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TXNIP |
| Specificity: |
This is a highly specific antibody against TXNIP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
140-190/391 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human TXNIP |
| Gene ID number: |
10628 |
| Swiss Prot: |
Q9H3M7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a suppressor of tumor cell growth, Functions as a transcriptional repressor, Inhibits the proteasomal degradation of DDIT4, Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, Required for the maturation of natural killer cells, and over-expression will induce G0/G1 cell cycle arrest, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1), blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
VDUP1 EST01027 HHCPA78 THIF ARRDC6 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
TXNIP Conjugated |
| Short name: |
Conjugated, TXNIP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, TXNIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16952 |
| Gene: |
TXNIP |
More about : TXNIP |
| Long gene name: |
thioredoxin interacting protein |
| Synonyms name: |
upregulated by 1, 25-dihydroxyvitamin D-3 thioredoxin binding protein 2 |
| Locus: |
1q21, 1 |
| Discovery year: |
2001-12-12 |
| GenBank acession: |
S73591 |
| Entrez gene record: |
10628 |
| Pubmed identfication: |
8086474 |
| RefSeq identity: |
NM_006472 |
| Classification: |
Alpha arrestins |
| Havana BLAST/BLAT: |
OTTHUMG00000013755 |