| Long name: |
TXNIP Primary Polyclonal Antibody |
| Also known as: |
TXNIP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TXNIP |
| Specificity: |
This is a highly specific antibody against TXNIP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
140-190/391 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TXNIP |
| Gene ID number: |
10628 |
| Swiss Prot: |
Q9H3M7 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a suppressor of tumor cell growth, Functions as a transcriptional repressor, Inhibits the proteasomal degradation of DDIT4, Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, Required for the maturation of natural killer cells, and over-expression will induce G0/G1 cell cycle arrest, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1), blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
EST01027, HHCPA78, TXNIP, Thioredoxin-binding protein 2, Thioredoxin-interacting protein, VDUP1, Vitamin D3 up-regulated protein 1, THIF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TXNIP |
| Short name: |
TXNIP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TXNIP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16952 |
| Gene: |
TXNIP |
More about : TXNIP |
| Long gene name: |
thioredoxin interacting protein |
| Synonyms: |
VDUP1 EST01027 HHCPA78 THIF ARRDC6 |
| Synonyms name: |
upregulated by 1, 25-dihydroxyvitamin D-3 thioredoxin binding protein 2 |
| Locus: |
1q21, 1 |
| Discovery year: |
2001-12-12 |
| GenBank acession: |
S73591 |
| Entrez gene record: |
10628 |
| Pubmed identfication: |
8086474 |
| RefSeq identity: |
NM_006472 |
| Classification: |
Alpha arrestins |
| Havana BLAST/BLAT: |
OTTHUMG00000013755 |