| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Tbk1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the Tbk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This Tbk1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9WUN2 |
| Purity: |
Antigen affinity |
| Description: |
Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1, Has a pivotal role in the innate immune response, It also seems to be a central factor in the induction of the antiviral interferon response, May function as an IKK kinase, Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization, This leads to production of alpha/beta interferons and the development of a cellular antiviral state, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes, Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B |
| Immunogen: |
A portion of amino acids 8-35 from the mouse protein was used as the immunogen for this Tbk1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Tbk1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Tbk1 |
| Short name: |
Tbk1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TANK-binding kinase 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11584 |
| Gene: |
TBK1 |
More about : TBK1 |
| Long gene name: |
TANK binding kinase 1 |
| Synonyms gene name: |
TANK-binding kinase 1 |
| Synonyms: |
NAK |
| Locus: |
12q14, 2 |
| Discovery year: |
2000-06-08 |
| GenBank acession: |
AF191838 |
| Entrez gene record: |
29110 |
| Pubmed identfication: |
10581243 10783893 |
| RefSeq identity: |
NM_013254 |
| Havana BLAST/BLAT: |
OTTHUMG00000168796 |