| Also known as: |
IKKE / TBK1 |
| Other names: |
NF-kB-activating kinase, NF-kappa-B-activating kinase, NF-kappa-B-activating kinase, Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, TANK-binding kinase 1, serine/threonine-protein kinase TBK1, serine/threonine-protein kinase TBK1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
IKKE |
| Gene name synonims: |
TBK1 |
| Other gene names: |
NAK, NAK, T2K, TBK1, TBK1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
72B587 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Bovine, Chicken, Dog, Due to limited knowledge and inability for testing each and every species, Gibbon, Gorilla, Hamster, Horse, Human (Homo sapiens), Insect, Monkey, Mouse (Mus musculus), Pig, Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Xenopus, Zebrafish <, the reactivity of the antibody may extend to other species which are not listed hereby, /b>, Bat, Drosophila (at least 90% immunogen sequence identity), Predicted Reactivity: <, b> |
| Specificity and cross-reactivity: |
It cross-reacts with mouse and rat IKKE and TBK1, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Human IKKE and TBK1 |
| Purification method: |
Protein G Purified |
| Form/Appearance: |
0, 0, Sourced in TCS, 05% BSA, 05% sodium azide, PBS |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
2 light chains, Each murine monoclonal anibody has his own affinity specific for the clone, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, Monoclonals of this antigen are available in different clones, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 72B587] IKKE / TBK1 |
| Short name: |
Mouse Monoclonal [clone 72B587] (IgG) IKKE / TBK1 Antibody |
| Technique: |
IgGs, Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens IKKE / TANK-binding kinase 1 (Antibody to), Mouse monoclonal [clonality 72B587] (Immunoglobulin G) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, TBK1 and IDBG-44993 and ENSG00000183735 and 29110, TBK1 and IDBG-634420 and ENSBTAG00000017401 and 533141, Tbk1 and IDBG-192882 and ENSMUSG00000020115 and 56480, this GO :0002218 and activation of innate immune response and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006954 and inflammatory response and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0009615 and response to virus and biological process this GO :0010008 and endosome membrane and cellular component this GO :0010629 and negative regulation of gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016772 and transferase activity, this GO :0003676 : nucleic acid binding, this GO :0003676 : nucleic acid binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0051219 : phosphoprotein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0051219 : phosphoprotein binding, transferring phosphorus-containing groups and molecular function this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032606 and type I interferon production and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0044565 and dendritic cell proliferation and biological process this GO :0045087 and innate immune response and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0051219 and phosphoprotein binding and molecular function this GO :0051607 and defense response to virus and biological process, TANK-binding kinase 1 |
| Identity: |
11584 |
| Gene: |
TBK1 |
More about : TBK1 |
| Long gene name: |
TANK binding kinase 1 |
| Synonyms gene name: |
TANK-binding kinase 1 |
| Synonyms: |
NAK |
| Locus: |
12q14, 2 |
| Discovery year: |
2000-06-08 |
| GenBank acession: |
AF191838 |
| Entrez gene record: |
29110 |
| Pubmed identfication: |
10581243 10783893 |
| RefSeq identity: |
NM_013254 |
| Havana BLAST/BLAT: |
OTTHUMG00000168796 |