| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MCP-2/CCL8 |
| Specificity: |
This antibody reacts specifically with MCP-2/CCL8 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CCL8 |
| Gene ID: |
6355 |
| Swiss Prot: |
P80075 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
May play a role in neoplasia and inflammatory host responses, The processed form MCP-2(6-76) does not show monocyte chemotactic activity, This protein can bind heparin, and also of CCL2 and CCL5 and CCL8, basophils and eosinophils, but inhibits the chemotactic effect most predominantly of CCL7, lymphocytes, Chemotactic factor that attracts monocytes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MCP-2 HC14 |
| Also known as: |
MCP-2/CCL8 Polyclonal Antibody |
| Other name: |
Anti-MCP-2/CCL8 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MCP-2/CCL8 |
| Short name: |
Anti-MCP-2/CCL8 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MCP-2/chemokine (C-C motif) ligand 8 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CCL8 and IDBG-40686 and ENSG00000108700 and 6355, CCL8 and IDBG-630945 and ENSBTAG00000014113 and 281044, Extracellular, HC14 and MCP-2 and MCP2 and SCYA10 and SCYA8, phospholipase activator activity, this GO :0004672 and protein kinase activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006816 and calcium ion transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006887 and exocytosis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0009615 and response to virus and biological process this GO :0016004 and phospholipase activator activity and molecular function this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0060326 and cell chemotaxis and biological process, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0008009 : chemokine activity and also this GO :0008201 : heparin binding and also this GO :0016004 : phospholipase activator activity, this GO :0008009 : chemokine activity, this GO :0008201 : heparin binding, this GO :0016004 : phospholipase activator activity, 788169, chemokine (C-C motif) ligand 8 |
| Identity: |
10635 |
| Gene: |
CCL8 |
More about : CCL8 |
| Long gene name: |
C-C motif chemokine ligand 8 |
| Synonyms gene: |
SCYA8 |
| Synonyms gene name: |
member 8 (monocyte chemotactic protein 2) chemokine (C-C motif) ligand 8 , small inducible cytokine subfamily A (Cys-Cys) |
| Locus: |
17q12 |
| Discovery year: |
1996-11-14 |
| GenBank acession: |
X99886 |
| Entrez gene record: |
6355 |
| Pubmed identfication: |
9119400 |
| RefSeq identity: |
NM_005623 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000132883 |