| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MCP-3/CCL7 |
| Specificity: |
based upon an 81% non-contiguous sequence similarity, there is a chance that this antibody will have a secondary cross-reaction with this the protein as well, Due to the homology of this protein to related protein CCL2, MCP-3/CCL7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MCP-3 |
| Gene ID: |
6354 |
| Swiss Prot: |
P80098 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also induces the release of gelatinase B, Augments monocyte anti-tumor activity, Binds to CCR1, CCR2 and CCR3, This protein can bind heparin, but not neutrophils, Chemotactic factor that attracts monocytes and eosinophils |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MCP-3 NC28 FIC MARC MCP3 |
| Also known as: |
MCP-3/CCL7 Polyclonal Antibody |
| Other name: |
Anti-MCP-3/CCL7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MCP-3/CCL7 |
| Short name: |
Anti-MCP-3/CCL7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MCP-3/chemokine (C-C motif) ligand 7 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CCL7 and IDBG-40580 and ENSG00000108688 and 6354, CCR2 chemokine receptor binding, Ccl7 and IDBG-204496 and ENSMUSG00000035373 and 20306, Extracellular, FIC and MARC and MCP-3 and MCP3 and NC28 and SCYA6 and SCYA7, this GO :0002548 and monocyte chemotaxis and biological process this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0008360 and regulation of cell shape and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031726 and CCR1 chemokine receptor binding and molecular function this GO :0031727 and CCR2 chemokine receptor binding and molecular function this GO :0048245 and eosinophil chemotaxis and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0071361 and cellular response to ethanol and biological process this GO :2000503 and positive regulation of natural killer cell chemotaxis and biological process, this GO :0008009 : chemokine activity, this GO :0008009 : chemokine activity and also this GO :0008201 : heparin binding and also this GO :0031726 : CCR1 chemokine receptor binding and also this GO :0031727 : CCR2 chemokine receptor binding, this GO :0008201 : heparin binding, this GO :0031726 : CCR1 chemokine receptor binding, this GO :0031727 : CCR2 chemokine receptor binding, chemokine (C-C motif) ligand 7 |
| Identity: |
10634 |
| Gene: |
CCL7 |
More about : CCL7 |
| Long gene name: |
C-C motif chemokine ligand 7 |
| Synonyms gene: |
SCYA6 SCYA7 |
| Synonyms gene name: |
small inducible cytokine A7 (monocyte chemotactic protein 3) chemokine (C-C motif) ligand 7 |
| Synonyms name: |
monocyte chemoattractant protein 3 monocyte chemotactic protein 3 |
| Locus: |
17q12 |
| Discovery year: |
1993-11-04 |
| GenBank acession: |
AF043338 |
| Entrez gene record: |
6354 |
| Pubmed identfication: |
8461011 |
| RefSeq identity: |
NM_006273 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000132889 |