MKK7 Antibody (MEK7)

Catalog number:	R31022 Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	MKK7 Antibody (MEK7)
Quantity:	0.1ml
Related search:	mkk kinase protein gene antibodies mapk deg thawing

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Category:	Antibody
Concentration:	2ml sterile DI water, 5mg/ml if reconstituted with 0
Form:	Antigen affinity purified
Conjugation:	Unconjugated
Clone:	Polyclonal antibody
Recognised antigen:	MKK7 (MEK7)
Host animal:	Rabbit (Oryctolagus cuniculus)
Clonality:	Polyclonal (rabbit origin)
Species reactivity:	Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications:	WB
Recommended dilutions:	5-1ug/ml, Western blot: 0
Notes:	Titration of the MKK7 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented use:	This MKK7 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #:	O14733
Purity:	Antigen affinity
Description:	JNKK2, MKK7 / Mek7 knockdown reduced p53 phosphorylation, Mek7 and MKK7, PRKMK7, Schramek et al, Schramek et al, The protein exists as six different isoforms with three possible N-termini (alpha, This protein is a member of the mitogen-activated protein kinase kinase family, also known as MAP kinase kinase 7 (MAPKK7), and gamma isoforms) and two possible C-termini (1 and 2 isoforms), and interfered with cell cycle arrest at G2/M, and tumors with a p53 mutation showed even higher MKK7 phosphorylation, beta, delayed p53 upregulation, is an enzyme that in humans is encoded by the MAP2K7 gene, the protein was activated in primary lung tumors, (2011) concluded that MKK7 / Mek7 exerts its tumor suppressive function through p53, (2011) showed that the doxorubicin-mediated DNA damage response in human A549 lung carcinoma cells caused rapid phosphorylation and upregulation of p53 (TP53), MAP2K7 (Mitogen-activated protein kinase kinase 7)
Immunogen:	mouse and rat), An amino acid sequence from the N-terminus of human MEK7/MKK7 (ARRRIDLNLDISPQRPR) was used as the immunogen for this MKK7 antibody (100% homologous in human
Storage:	Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MKK7 antibody can be stored for up to one month at 4oC, After reconstitution
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target:	MKK7 (MEK7)
Short name:	MKK7 Antibody (MEK7)
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	MKK7 (Antibody to) (MEK7)
Alternative technique:	antibodies
Identity:	6847
Gene:	MAP2K7 | More about : MAP2K7
Long gene name:	mitogen-activated protein kinase kinase 7
Synonyms gene:	PRKMK7
Synonyms:	MKK7 Jnkk2
Locus:	19p13, 2
Discovery year:	1998-04-28
GenBank acession:	AF006689
Entrez gene record:	5609
Pubmed identfication:	9312068
Classification:	Mitogen-activated protein kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000137368

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