MKK7/ERK7 Antibody, FITC Conjugated

Catalog number:	bs-1979R-FITC Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	MKK7/ERK7 Antibody, FITC Conjugated
Quantity:	100ul
Related search:	antibody antibodies conjugated mapkmkk protein pathway residue fluorescent component

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Long name:	FITC Conjugated, MKK7/ERK7 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Anti-FITC Antibody
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	MKK7/ERK7
Specificity:	This is a highly specific antibody against MKK7/ERK7
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	300-350/419
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human MKK7
Gene ID number:	5609
Swiss Prot:	O14733
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway, Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines, MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue, MAPK9/JNK2 and MAPK10/JNK3, The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, With MAP2K4/MKK4, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif, including the release cytochrome c, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, leading to apoptosis, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation, Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	494nm/518nm
Synonyms:	MKK7 Jnkk2
Properties:	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	MKK7/ERK7 Conjugated
Short name:	FITC Conjugated, MKK7/ERK7 Antibody
Technique:	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	FITC
Alternative name:	fluorecein coupled, MKK7/ERK7 (Antibody to)
Alternative technique:	antibodies
Identity:	6847
Gene:	MAP2K7 | More about : MAP2K7
Long gene name:	mitogen-activated protein kinase kinase 7
Synonyms gene:	PRKMK7
Locus:	19p13, 2
Discovery year:	1998-04-28
GenBank acession:	AF006689
Entrez gene record:	5609
Pubmed identfication:	9312068
Classification:	Mitogen-activated protein kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000137368

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