MKK7/ERK7 Antibody, Cy3 Conjugated

Catalog number:	bs-1979R-Cy3 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	MKK7/ERK7 Antibody, Cy3 Conjugated
Quantity:	100ul
Related search:	antibody antibodies mapkmkk protein pathway residue mapkjnk transduction

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Long name:	Cy3 Conjugated, MKK7/ERK7 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	cy3 conjugation kit
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	MKK7/ERK7
Specificity:	This is a highly specific antibody against MKK7/ERK7
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	300-350/419
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human MKK7
Gene ID number:	5609
Swiss Prot:	O14733
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway, Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines, MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue, MAPK9/JNK2 and MAPK10/JNK3, The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, With MAP2K4/MKK4, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif, including the release cytochrome c, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, leading to apoptosis, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation, Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	512, 550nm/570, 615nm
Synonyms:	MKK7 Jnkk2
Properties:	1 of the MKK7/ERK7 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	MKK7/ERK7 Conjugated
Short name:	Conjugated, MKK7/ERK7 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy3
Alternative name:	cyanine 3 coupled, MKK7/ERK7 (Antibody to)
Alternative technique:	antibodies
Identity:	6847
Gene:	MAP2K7 | More about : MAP2K7
Long gene name:	mitogen-activated protein kinase kinase 7
Synonyms gene:	PRKMK7
Locus:	19p13, 2
Discovery year:	1998-04-28
GenBank acession:	AF006689
Entrez gene record:	5609
Pubmed identfication:	9312068
Classification:	Mitogen-activated protein kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000137368

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