| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
5-Lipoxygenase |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the 5-Lipoxygenase antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This 5-Lipoxygenase antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
240 |
| Purity: |
Antigen affinity |
| Description: |
ALOX5 also transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases, ALOX5 plays a dual role in the synthesis of leukotrienes from arachidonic acid, It is a member of the lipoxygenase family of enzymes, It is involved in lung vascular tone regulation and in the development of chronic pulmonary hypertension in hypoxic rodent models, It is mapped to 10q11, Its position within the nucleus of resting cells determines the capacity to generate LTB4 upon subsequent activation, also known as 5-LOX or 5-LO, is an enzyme that in humans is encoded by the ALOX5 gene, 21, Arachidonate 5-lipoxygenase |
| Immunogen: |
Human partial recombinant protein (AA 120-483) was used as the immunogen for this 5-Lipoxygenase antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the 5-Lipoxygenase antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
5-Lipoxygenase |
| Short name: |
5-Lipoxygenase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
5-Lipoxygenase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
435 |
| Gene: |
ALOX5 |
More about : ALOX5 |
| Long gene name: |
arachidonate 5-lipoxygenase |
| Synonyms: |
5-LOX |
| Locus: |
10q11, 21 |
| Discovery year: |
1992-07-10 |
| GenBank acession: |
J03571 |
| Entrez gene record: |
240 |
| Pubmed identfication: |
2565035 |
| Classification: |
Arachidonate lipoxygenases |
| Havana BLAST/BLAT: |
OTTHUMG00000018081 |