| Long name: |
15 Lipoxygenase 1 Primary Polyclonal Antibody |
| Also known as: |
15 Lipoxygenase 1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
15 Lipoxygenase 1 |
| Specificity: |
This is a highly specific antibody against 15 Lipoxygenase 1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
610-662/662 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ALOX15/15 Lipoxygenase 1 |
| Gene ID number: |
246 |
| Swiss Prot: |
P16050 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid, Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE, Finally, In addition to its role in the immune and inflammatory responses, In parallel, May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3, May also play a role in endoplasmic reticulum stress response and the regulation of bone mass, May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway, Probably plays an important role in the immune and inflammatory responses, Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes, including macrophage function, it is also involved in the cellular response to IL13/interleukin-13, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4, may regulate actin polymerization which is crucial for several biological processes, Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
12/15-lipoxygenase, 15-LOX, 15-LOX-1, 15LOX-1, ALOX15, Arachidonate 12-lipoxygenase, Arachidonate 15-lipoxygenase, Arachidonate omega-6 lipoxygenase, LOG15, leukocyte-type, 12-LOX |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
15 Lipoxygenase 1 |
| Short name: |
15 Lipoxygenase 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
15 Lipoxygenase 1 (Antibody to) |
| Alternative technique: |
antibodies |