HPV16 E6 protein (2E3) Antibody, Cy7 Conjugated

Catalog number:	bsm-0990M-Cy7 Buy Now
Price:	333 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	HPV16 E6 protein (2E3) Antibody, Cy7 Conjugated
Quantity:	0.1ml
Related search:	protein hpv antibodies host cell deg

More details Need more?:

Long name:	Cy7 Conjugated, HPV16 E6 protein (2E3) Monoclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Cy7
Host Organism:	Mouse (Mus musculus)
Target Antigen:	HPV16 E6 protein
Specificity:	This is a highly specific antibody against HPV16 E6 protein
Modification:	Unmodified
Modification site:	None
Clonality:	Monoclonal
Clone:	2000
Concentration:	1ug per 1ul
Immunogen_range:	85-158/158
Source:	KLH conjugated synthetic peptide derived from HPV16 E6 protein
Gene ID number:	1489078
Swiss Prot:	P03126
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Virus
Crossreactive species details:	HPV16
Antigen background:	Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development, E6 also inhibits immune response by interacting with host IRF3 and TYK2, E6 associates with host E6-AP ubiquitin-protein ligase, Fas-associated death domain-containing protein (FADD) and procaspase 8, In turn, Other cellular targets including Bak, The complex E6/E6P targets several other substrates to degradation via the proteasome including host NFX1-91, The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization, These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway, a repressor of human telomerase reverse transcriptase (hTERT), and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation, are degraded by E6/E6AP causing inhibition of apoptosis, Plays a major role in the induction and maintenance of cellular transformation
Purification method:	Purified by Protein G
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	743nm/767nm
Synonyms:	E6, Protein E6
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated:	These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene target:	HPV16 E6 protein (2E3) Conjugated
Short name:	Conjugated, HPV16 E6 protein (2E3) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy7
Alternative name:	cyanine 7 coupled, HPV16 E6 protein (2E3) (Antibody to)
Alternative technique:	antibodies

• #protein
• #hpv
• #antibodies
• #host
• #cell
• #deg