| known also as: |
Anti-GOAT ANTI HUMAN NALP3 (C-TERMINAL) |
| known also as: |
Caprine ANTI HUMAN NALP3 (C-TERMINAL) |
| known also as: |
Caprinae ANTI Homo sapiens NALP3 (C-TERMINAL) |
| known also as: |
NALP3 |
| Other names: |
Angiotensin/vasopressin receptor AII/AVP-like, CLR1, Caterpiller protein 1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, LRR and PYD containing protein 3, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3 isoform a, NACHT, NACHT, NACHT, NACHT domain-, NLR family, PYRIN-containing APAF1-like protein 1, PYRIN-containing APAF1-like protein 1, and PYD-containing protein 3, caterpiller protein 1, cold autoinflammatory syndrome 1 protein, cryopyrin, leucine rich repeat and pyrin domain containing 3, leucine-rich repeat-, nucleotide-binding oligomerization domain, pyrin domain containing 3, 1, 1, 1, NACHT |
| Gene name: |
NALP3 |
| Other gene names: |
AGTAVPRL, AII, AVP, C1orf7, C1orf7, CIAS1, CIAS1, CLR1, CLR1, FCAS, FCU, MWS, NALP3, NALP3, NLRP3, PYPAF1, PYPAF1, 1, 1, NLRP3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
LRR and PYD domains-containing protein 3 (NALP3), Muckle-Wells syndrome (MWS), NALP3 can also be detected in non-keratinizing epithelia of oropharynx, Research indicates that NALP3 may function as an activator of NF-kappaB signalling and play a role in the regulation of inflammation and apoptosis, _x000D_Mutations in the NALP3 gene have been associated with familial cold autoinflammatory syndrome (FCAS), _x000D_NALP3 is involved in inflammation and immune response, _x000D_NALP3 is strongly expressed in polymorphonuclear cells, a cytoplasmic protein belonging to the NLRP family, and neonatal-onset multisystem inflammatory disease (NOMID), chronic infantile neurological cutaneous and articular (CINCA) syndrome, esophagus and ectocervix and in the urothelial layer of the bladder, osteoblasts and chondrocytes, NALP3 This item recognises human NACHT |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC), ELISA (EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
NALP3 |
| Short name: |
GOAT ANTI HUMAN NALP3 (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens NALP3 (C-TERMINAL) (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
16400 |
| Gene: |
NLRP3 |
More about : NLRP3 |
| Long gene name: |
NLR family pyrin domain containing 3 |
| Synonyms gene: |
C1orf7 CIAS1 |
| Synonyms gene name: |
cold autoinflammatory syndrome 1 |
| Synonyms: |
AGTAVPRL AII AVP FCAS FCU NALP3 PYPAF1 MWS CLR1, 1 |
| Synonyms name: |
Cryopyrin nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 |
| Locus: |
1q44 |
| Discovery year: |
2001-08-28 |
| GenBank acession: |
AF054176 |
| Entrez gene record: |
114548 |
| Pubmed identfication: |
10741953 |
| RefSeq identity: |
NM_004895 |
| Classification: |
NLR family Pyrin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000040647 |
| Locus Specific Databases: |
INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations LRG_197 |