| known also as: |
Anti-Goat Polyclonal to Human NALP3 / NLRP3 |
| known also as: |
Caprine PAb to Human NALP3 / NLRP3 |
| known also as: |
Caprinae Polyclonal to Homo sapiens NALP3 / NLRP3 |
| known also as: |
NALP3 / NLRP3 |
| known also as: |
AGTAVPRL, AII, C1orf7, CIAS1, CLR1, Caterpiller protein 1, Cryopyrin, FCAS, FCU, Human NALP3, MWS, NALP3, NLRP3, NLRP3, PYPAF1, 1, 1, Anti-NALP3 / NLRP3 Antibody (Internal) IHC-plus |
| Other names: |
Angiotensin/vasopressin receptor AII/AVP-like, CLR1, Caterpiller protein 1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, LRR and PYD containing protein 3, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3 isoform a, NACHT, NACHT, NACHT, NACHT domain-, NLR family, PYRIN-containing APAF1-like protein 1, PYRIN-containing APAF1-like protein 1, and PYD-containing protein 3, caterpiller protein 1, cold autoinflammatory syndrome 1 protein, cryopyrin, leucine rich repeat and pyrin domain containing 3, leucine-rich repeat-, nucleotide-binding oligomerization domain, pyrin domain containing 3, 1, 1, 1, NACHT |
| Gene name: |
NALP3 |
| Gene name synonims: |
NLRP3 |
| Other gene names: |
AGTAVPRL, AII, AVP, C1orf7, C1orf7, CIAS1, CIAS1, CLR1, CLR1, FCAS, FCAS1, FCU, MWS, NALP3, NALP3, NLRP3, PYPAF1, PYPAF1, 1, 1, NLRP3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Gorilla, Human, Monkey <, Pig (at least 90% immunogen sequence identity), /b>, Bat, Gibbon, Predicted Reactivity: <, b> |
| Specificity and cross-reactivity: |
NP_001120933, NP_001120934, NP_001230062, NP_899632, Reported variants represent identical protein (NP_004886, This antibody is expected to recognise all five reported isoforms (NP_004886, 1, 1, 1, 1), 1), 3, 3 and NP_001073289, Human NLRP3 |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 0, pH 7, 02% sodium azide, 3, 5% BSA, Tris-buffered saline |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Minimize freezing and thawing, productone should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested for:: |
ELISA (EIA), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| Latin name: |
Capra aegagrus hircus |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NALP3 / NLRP3 |
| Short name: |
Goat Polyclonal NALP3 / NLRP3 Antibody |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, each identifying a different , goats, whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host: |
It are very good secondary antibodies that are affinity purified and have a good affinity themselves too, Often KLH is coupled to the antigen so anti KLH can be present in the vial, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection, Goat |
| Species: |
Goats, Humans, Human |
| Alternative name: |
pyrin domain containing 3 (Antibody to), sapiens NALP3 / NLR family, caprine polyclonal to H |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cytoplasm, NLRP3 and IDBG-107914 and ENSG00000162711 and 114548, NLRP3 and IDBG-645402 and ENSBTAG00000001273 and 538639, Nlrp3 and IDBG-178924 and ENSMUSG00000032691 and 216799, leucine rich repeat containing receptor signaling pathway and biological process this GO :0042347 and negative regulation of NF-kappaB import into nucleus and biological process this GO :0042834 and peptidoglycan binding and molecular function this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0044546 and NLRP3 inflammasome complex assembly and biological process this GO :0045087 and innate immune response and biological process this GO :0050701 and interleukin-1 secretion and biological process this GO :0050713 and negative regulation of interleukin-1 beta secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051607 and defense response to virus and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0072559 and NLRP3 inflammasome complex and cellular component, peptidoglycan binding, pyrin domain containing 3, this GO :0002674 and negative regulation of acute inflammatory response and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006952 and defense response and biological process this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0009595 and detection of biotic stimulus and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032611 and interleukin-1 beta production and biological process this GO :0032621 and interleukin-18 production and biological process this GO :0035872 and nucleotide-binding domain, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0042834 : peptidoglycan binding, this GO :0005524 : ATP binding, this GO :0042834 : peptidoglycan binding, NLR family |
| Identity: |
16400 |
| Gene: |
NLRP3 |
More about : NLRP3 |
| Long gene name: |
NLR family pyrin domain containing 3 |
| Synonyms gene: |
C1orf7 CIAS1 |
| Synonyms gene name: |
cold autoinflammatory syndrome 1 |
| Synonyms: |
AGTAVPRL AII AVP FCAS FCU NALP3 PYPAF1 MWS CLR1, 1 |
| Synonyms name: |
Cryopyrin nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 |
| Locus: |
1q44 |
| Discovery year: |
2001-08-28 |
| GenBank acession: |
AF054176 |
| Entrez gene record: |
114548 |
| Pubmed identfication: |
10741953 |
| RefSeq identity: |
NM_004895 |
| Classification: |
NLR family Pyrin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000040647 |
| Locus Specific Databases: |
INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations LRG_197 |