| known also as: |
Angiotensin/Vasopressin Recepto, C1orf7, CIAS1, CIAS1, CLR1, CT (NACHT-, Caterpiller Protein 1, Cold Autoinflammatory Syndrome 1 Protein, Cryopyrin, LRR- and PYD-Containing Protein 3, NLRP3, PYPAF1, PYPAF1, PYRIN-Containing APAF1-like Protein 1, 1, 1, Anti-NALP3 |
| known also as: |
Angiotensin/Vasopressin Recepto, C1orf7, CIAS1, CIAS1, CLR1, CT (NACHT-, Caterpiller Protein 1, Cold Autoinflammatory Syndrome 1 Protein, Cryopyrin, LRR- and PYD-Containing Protein 3, NLRP3, PYPAF1, PYPAF1, PYRIN-Containing APAF1-like Protein 1, 1, 1, NALP3 |
| known also as: |
Angiotensin/Vasopressin Recepto, C1orf7, CIAS1, CIAS1, CLR1, CT (NACHT-, Caterpiller Protein 1, Cold Autoinflammatory Syndrome 1 Protein, Cryopyrin, LRR- and PYD-Containing Protein 3, NLRP3, PYPAF1, PYPAF1, PYRIN-Containing APAF1-like Protein 1, 1, 1, NALP3 |
| known also as: |
NALP3 |
| known also as: |
Angiotensin/Vasopressin Recepto, C1orf7, CIAS1, CIAS1, CLR1, CT (NACHT-, Caterpiller Protein 1, Cold Autoinflammatory Syndrome 1 Protein, Cryopyrin, LRR- and PYD-Containing Protein 3, NLRP3, PYPAF1, PYPAF1, PYRIN-Containing APAF1-like Protein 1, 1, 1, Anti -NALP3 |
| Other names: |
AII/AVP receptor-like, LRR and PYD containing protein 3, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3 isoform c, N/A, NACHT, NACHT, NACHT domain-, NLR family, OTTHUMP00000038408, OTTHUMP00000038409, OTTHUMP00000038410, OTTHUMP00000038411, OTTHUMP00000230825, PYRIN-containing APAF1-like protein 1, and PYD-containing protein 3, caterpiller protein 1, cold autoinflammatory syndrome 1 protein, cryopyrin, leucine rich repeat and pyrin domain containing 3, leucine-rich repeat-, nucleotide-binding oligomerization domain, pyrin domain containing 3, 1, NACHT |
| Other gene names: |
AGTAVPRL, AII, AVP, C1orf7, CIAS1, CIAS1, CLR1, FCAS, FCU, FLJ95925, MWS, N/A, NALP3, PYPAF1, 1, NLRP3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Goat |
| Species reactivity: |
Rat, Human |
| Specificity and cross-reactivity: |
LRR and PYD domains-containing protein 3 (NALP3), Species crossreactivity: rat, Recognizes human NACHT |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 0, pH 7, 02% sodium azide, 3, 5% BSA, Supplied as a liquid in TBS |
| Storage and shipping: |
Aliquot to avoid repeated freezing and thawing, Aliquots are stable for at least 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunohistochemistry (IHC), ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
Angiotensin/Vasopressin Recepto, C1orf7, CIAS1, CIAS1, CLR1, CT (NACHT LRR PYD Protein 3, Caterpiller Protein 1, Cold Autoinflammatory Syndrome 1 Protein, Cryopyrin, NLRP3, PYPAF1, PYPAF1, PYRIN APAF1-like Protein 1, 1, 1, NALP3 |
| Short name: |
Angiotensin/Vasopressin Recepto, C1orf7, CIAS1, CIAS1, CLR1, CT (NACHT- LRR- PYD- Protein 3, Caterpiller Protein 1, Cold Autoinflammatory Syndrome 1 Protein, Cryopyrin, NLRP3, PYPAF1, PYPAF1, PYRIN- APAF1-like Protein 1, 1, 1, NALP3 |
| Alternative name: |
Angiotensin/Vasopressin Recepto, C1orf7, CIAS1, CIAS1, CLR1, CT (NACHT-, Caterpiller Protein 1, Cold Autoinflammatory Syndrome 1 Protein, Cryopyrin, LRR- and PYD-Containing Protein 3, NLR family, PYPAF1, PYPAF1, PYRIN-Containing apoptotic peptidase activating factor 1-like Protein 1, pyrin domain containing 3, 1, 1, NALP3 |
| Alternative to gene target: |
ADP binding, APAF-1 and CED4, APAF1 and IDBG-52364 and ENSG00000120868 and 317, APAF1 and IDBG-636787 and ENSBTAG00000021661 and 537782, Apaf1 and IDBG-185032 and ENSMUSG00000019979 and 11783, Cytoplasm, NLR family, NLRP3 and IDBG-107914 and ENSG00000162711 and 114548, NLRP3 and IDBG-645402 and ENSBTAG00000001273 and 538639, Nlrp3 and IDBG-178924 and ENSMUSG00000032691 and 216799, leucine rich repeat containing receptor signaling pathway and biological process this GO :0042347 and negative regulation of NF-kappaB import into nucleus and biological process this GO :0042834 and peptidoglycan binding and molecular function this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0044546 and NLRP3 inflammasome complex assembly and biological process this GO :0045087 and innate immune response and biological process this GO :0050701 and interleukin-1 secretion and biological process this GO :0050713 and negative regulation of interleukin-1 beta secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051607 and defense response to virus and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0072559 and NLRP3 inflammasome complex and cellular component, nuclei, peptidoglycan binding, pyrin domain containing 3, this GO :0000166 and nucleotide binding and molecular function this GO :0001843 and neural tube closure and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006952 and defense response and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007399 and nervous system development and biological process this GO :0007420 and brain development and biological process this GO :0008635 and activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0030900 and forebrain development and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043293 and apoptosome and cellular component this GO :0043531 and ADP binding and molecular function this GO :0051402 and neuron apoptotic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072432 and response to G1 DNA damage checkpoint signaling and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1902510 and regulation of apoptotic DNA fragmentation and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, this GO :0000166 : nucleotide binding, this GO :0000166 : nucleotide binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0042802 : identical protein binding and also this GO :0043531 : ADP binding, this GO :0002674 and negative regulation of acute inflammatory response and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006952 and defense response and biological process this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0009595 and detection of biotic stimulus and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032611 and interleukin-1 beta production and biological process this GO :0032621 and interleukin-18 production and biological process this GO :0035872 and nucleotide-binding domain, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0042834 : peptidoglycan binding, this GO :0005524 : ATP binding, this GO :0005524 : ATP binding, this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0042802 : identical protein binding, this GO :0042834 : peptidoglycan binding, this GO :0043531 : ADP binding, apoptotic peptidase activating factor 1 |
| Identity: |
16400 |
| Gene: |
NLRP3 |
More about : NLRP3 |
| Long gene name: |
NLR family pyrin domain containing 3 |
| Synonyms gene: |
C1orf7 CIAS1 |
| Synonyms gene name: |
cold autoinflammatory syndrome 1 |
| Synonyms: |
AGTAVPRL AII AVP FCAS FCU NALP3 PYPAF1 MWS CLR1, 1 |
| Synonyms name: |
Cryopyrin nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 |
| Locus: |
1q44 |
| Discovery year: |
2001-08-28 |
| GenBank acession: |
AF054176 |
| Entrez gene record: |
114548 |
| Pubmed identfication: |
10741953 |
| RefSeq identity: |
NM_004895 |
| Classification: |
NLR family Pyrin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000040647 |
| Locus Specific Databases: |
INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations LRG_197 |