| Long name: |
Cy3 Conjugated, Factor XII heavy chain Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Factor XII heavy chain |
| Specificity: |
This is a highly specific antibody against Factor XII heavy chain |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Coagulation factor XIIa heavy chain |
| Gene ID number: |
2161 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged, It activates coagulation factors VII and XI, Jul 2008], On activation, Prekallikrein is cleaved by factor XII to form kallikrein, The active factor XIIa participates in the initiation of blood coagulation, The heavy chain contains two fibronectin-type domains, This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain, [provided by RefSeq, a kringle domain and a proline-rich domain, and the generation of bradykinin and angiotensin, fibrinolysis, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain, two epidermal growth factor (EGF)-like domains, whereas the light chain contains only a catalytic domain, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa, This gene encodes coagulation factor XII which circulates in blood as a zymogen |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
Coagulation factor XII, Coagulation factor XIIa heavy chain, Coagulation factor XIIa heavy chain, F12, F12 deficiency, FA12_HUMAN, Factor XII deficiency, Factor XII heavy chain, HAE3, HAEX, HAF, HAF deficiency, Hageman factor, Factor XII |
| Properties: |
1 of the Factor XII heavy chain Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Factor XII heavy chain Conjugated |
| Short name: |
Conjugated, Factor XII heavy chain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Factor XII heavy epitope (Antibody to) |
| Alternative technique: |
antibodies |