| Long name: |
Cy3 Conjugated, Factor I heavy chain Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Factor I heavy chain |
| Specificity: |
This is a highly specific antibody against Factor I heavy chain |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human Complement factor I heavy chain |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CR1 or MCP are required for C3b cleavage, Complement protein Factor I is a key serine protease that modulates the complement cascade by regulating the levels of C3 convertases, Factor H, Factor I is a serine protease with a high degree of specificity for C3b and C4b, It circulates in plasma as a heavily N-glycosylated heterodimer made up of two disulfide linked chains, It requires protein cofactors for cleavage of these complement proteins, There are three pathways of complement activation: the classical pathway, and C4bp or CR1 are required for C4b cleavage, each carrying three N-linked oligosaccharide chains that may have both structural and functional roles in the interactions with the natural substrate and the cofactor during catalysis, lectin pathway and alternative pathway, The complement pathway is an important host defense system that contributes to both innate and acquired immunity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
, AHUS3, C3B/C4B inactivator, C3BINA, C3b INA, C3b inactivator, CFAI_HUMAN, CFI, Complement component I, Complement control protein factor I, Complement factor I, Complement factor I heavy chain, F1, FI, FactorI, Heavy chain of factor I, I factor, KAF, Konglutinogen activating factor, OTTHUMP00000219728, factor I, Factor I heavy chain |
| Properties: |
1 of the Factor I heavy chain Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Factor I heavy chain Conjugated |
| Short name: |
Conjugated, Factor I heavy chain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Factor I heavy epitope (Antibody to) |
| Alternative technique: |
antibodies |