| Long name: |
ALEXA FLUOR 647 Conjugated, Factor XII heavy chain Antibody |
| Also known as: |
Anti-Factor XII heavy chain PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Factor XII heavy chain |
| Specificity: |
This is a highly specific antibody against Factor XII heavy chain |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Coagulation factor XIIa heavy chain |
| Gene ID Number: |
2161 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged, It activates coagulation factors VII and XI, Jul 2008], On activation, Prekallikrein is cleaved by factor XII to form kallikrein, The active factor XIIa participates in the initiation of blood coagulation, The heavy chain contains two fibronectin-type domains, This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain, [provided by RefSeq, a kringle domain and a proline-rich domain, and the generation of bradykinin and angiotensin, fibrinolysis, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain, two epidermal growth factor (EGF)-like domains, whereas the light chain contains only a catalytic domain, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa, This gene encodes coagulation factor XII which circulates in blood as a zymogen |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
Coagulation factor XII, Coagulation factor XIIa heavy chain, Coagulation factor XIIa heavy chain, F12, F12 deficiency, FA12_HUMAN, Factor XII deficiency, Factor XII heavy chain, HAE3, HAEX, HAF, HAF deficiency, Hageman factor, Factor XII |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Factor XII heavy chain Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Factor XII heavy chain |
| Short name: |
Factor XII heavy chain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Factor XII heavy epitope (Antibody to) |
| Alternative technique: |
antibodies |