| Catalog number: | bs-9380R-A594 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | Midline 1 Antibody, ALEXA FLUOR 594 |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | ALEXA FLUOR 594 Conjugated, Midline 1 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-Midline-1 PAb ALEXA FLUOR 594 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 594, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Midline-1 |
| Specificity: | This is a highly specific antibody against Midline-1 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Midline-1/RNF59 |
| Gene ID Number: | 4281 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Defects in MID1 are the cause of Opitz syndrome type I (OS-I), It also interacts with IGBP1 (Lymphocyte signaling protein A4), It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2, Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation, OS-I is an X-linked recessive disorder characterized by hypertelorism, OS-I mutations produce proteins with a decreased affinity for microtubules, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1, developmental delay and congenital heart defects, genital-urinary defects such as hypospadias in males and splayed labia in females, imperforate anus, lip-palate-laryngotracheal clefts, one B30, one COS domain, one fibronectin type-III domain and one RING-type zinc finger, 2/SPRY domain, Midline-1 (Tripartite motif-containing protein 18 |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | OS FXY TRIM18 RNF59 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: | Alexa conjugate 1 |
| Gene target: | Midline 1 |
| Short name: | Midline 1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 594 |
| Alternative name: | ALEXA FLUOR 594, Midline 1 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 7095 |
| Gene: | MID1 | More about : MID1 |
| Long gene name: | midline 1 |
| Synonyms name: | Opitz/BBB syndrome |
| Locus: | Xp22 |
| Discovery year: | 1997-12-12 |
| GenBank acession: | Y13667 |
| Pubmed identfication: | 9354791 9425238 |
| Classification: | Tripartite motif containing Ring finger proteins Fibronectin type III domain containing |
| Havana BLAST/BLAT: | OTTHUMG00000021127 |
| Locus Specific Databases: | Mental Retardation database |
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