p53 (FL-393) Antibody, Biotin Conjugated

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Catalog number: bs-8687R-Biotin
Price: 1413 €
Supplier: acr
Product name: p53 (FL-393) Antibody, Biotin Conjugated
Quantity: 0,25 mg
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More details :

Long name: Biotin Conjugated, p53 (FL-393) Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Biotinylated
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: p53 FL-393
Specificity: This is a highly specific antibody against p53 FL-393
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: Full length human p53 protein
Gene ID number: 7157
Tested applications: IHC-P, WB
Recommended dilutions: IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: MDM2, MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, Mutations in the DNA-binding domain (DBD) of p53, a DNA-binding, amino acids 110-286, and cell cycle control mechanisms, can compromise energetically-favorable association with cis elements and are implicated in several human cancers, cell differentiation, including phosphorylation and acetylation, oligomerization domain- and transcription activation domain-containing tumor suppressor, p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, p53 localizes to the nucleus, thereby influencing programmed cell death, upregulates growth arrest and apoptosis-related genes in response to stress signals, where it poly-ubiquitinates p53 for proteasome targeting, yet can be chaperoned to the cytoplasm by the negative regulator, p53
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms: Phosphoprotein p53, TP53, TRP53, Transformation related protein 53, Tumor protein p53, Tumour Protein p53, p53, p53 Cellular Tumor Antigen, p53 Tumor Suppressor, LFS1
Properties: Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target: p53 (FL-393) Conjugated
Short name: Conjugated, p53 (FL-393) Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Biotin
Alternative name: biotinilated coupled, p53 (FL-393) (Antibody to)
Alternative technique: antibodies

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