| Long name: |
ALEXA FLUOR 350 Conjugated, p53 (FL-393) Polyclonal Antibody |
| Also known as: |
Anti-p53 FL-393 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
p53 FL-393 |
| Specificity: |
This is a highly specific antibody against p53 FL-393 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
Full length human p53 protein |
| Gene ID Number: |
7157 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
MDM2, MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, Mutations in the DNA-binding domain (DBD) of p53, a DNA-binding, amino acids 110-286, and cell cycle control mechanisms, can compromise energetically-favorable association with cis elements and are implicated in several human cancers, cell differentiation, including phosphorylation and acetylation, oligomerization domain- and transcription activation domain-containing tumor suppressor, p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, p53 localizes to the nucleus, thereby influencing programmed cell death, upregulates growth arrest and apoptosis-related genes in response to stress signals, where it poly-ubiquitinates p53 for proteasome targeting, yet can be chaperoned to the cytoplasm by the negative regulator, p53 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
Phosphoprotein p53, TP53, TRP53, Transformation related protein 53, Tumor protein p53, Tumour Protein p53, p53, p53 Cellular Tumor Antigen, p53 Tumor Suppressor, LFS1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
p53 (FL-393) |
| Short name: |
p53 (FL-393) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, p53 (FL-393) (Antibody to) |
| Alternative technique: |
antibodies |