| Long name: |
ALEXA FLUOR 647 Conjugated, p53 (FL-393) Polyclonal Antibody |
| Also known as: |
Anti-p53 FL-393 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
p53 FL-393 |
| Specificity: |
This is a highly specific antibody against p53 FL-393 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
Full length human p53 protein |
| Gene ID Number: |
7157 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
MDM2, MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, Mutations in the DNA-binding domain (DBD) of p53, a DNA-binding, amino acids 110-286, and cell cycle control mechanisms, can compromise energetically-favorable association with cis elements and are implicated in several human cancers, cell differentiation, including phosphorylation and acetylation, oligomerization domain- and transcription activation domain-containing tumor suppressor, p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, p53 localizes to the nucleus, thereby influencing programmed cell death, upregulates growth arrest and apoptosis-related genes in response to stress signals, where it poly-ubiquitinates p53 for proteasome targeting, yet can be chaperoned to the cytoplasm by the negative regulator, p53 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
Phosphoprotein p53, TP53, TRP53, Transformation related protein 53, Tumor protein p53, Tumour Protein p53, p53, p53 Cellular Tumor Antigen, p53 Tumor Suppressor, LFS1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the p53 (FL-393) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
p53 (FL-393) |
| Short name: |
p53 (FL-393) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, p53 (FL-393) (Antibody to) |
| Alternative technique: |
antibodies |