| Long name: |
Biotin Conjugated, FBXL11 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FBXL11 |
| Specificity: |
This is a highly specific antibody against FBXL11 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human FBXL11 |
| Gene ID number: |
22992 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Additionally, CXXC8, Expressed ubiquitously with highest expression in testis, F-box proteins are members of a large family that regulate the cell cycle, FBL11, FBL11 functions to demethylate the Lys-36 residue of histone H3, FBL11 is thought to promote the ubiquitination and subsequent degradation of various phosphorylated proteins, JHDM1A (JmjC domain-containing histone demethylation protein 1A) or LILINA, KDM2A, Three isoforms of FBL11 exist due to alternative splicing events, also known as FBXL11 (F-box and leucine-rich repeat protein 11), for degradation by the proteasome after ubiquitination, immune response, is a 1, ovary and brain, signaling cascades and developmental programs by targeting proteins, such as cyclins, thereby modulating the histone code, 162 amino acid member of the F-box protein family that contains one F-box domain and localizes to the nucleus, F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KIAA1004 FBL11 LILINA DKFZP434M1735 FBL7 FLJ00115 CXXC8 JHDM1A |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FBXL11 Conjugated |
| Short name: |
Conjugated, FBXL11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, FBXL11 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13606 |
| Gene: |
KDM2A |
More about : KDM2A |
| Long gene name: |
lysine demethylase 2A |
| Synonyms gene: |
FBXL11 |
| Synonyms gene name: |
F-box and leucine-rich repeat protein 11 lysine (K)-specific demethylase 2A |
| Synonyms name: |
F-box protein FBL11 jumonji C domain-containing histone demethylase 1A |
| Locus: |
11q13, 2 |
| Discovery year: |
2000-09-27 |
| GenBank acession: |
BC047486 |
| Entrez gene record: |
22992 |
| Pubmed identfication: |
10231032 10531037 |
| RefSeq identity: |
NM_012308 |
| Classification: |
PHD finger proteins Lysine demethylases F-box and leucine rich repeat proteins Zinc fingers CXXC-type |
| Havana BLAST/BLAT: |
OTTHUMG00000167103 |