| Long name: |
FBXL11 Primary Polyclonal Antibody |
| Also known as: |
FBXL11 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FBXL11 |
| Specificity: |
This is a highly specific antibody against FBXL11 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FBXL11 |
| Gene ID number: |
22992 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Additionally, CXXC8, Expressed ubiquitously with highest expression in testis, F-box proteins are members of a large family that regulate the cell cycle, FBL11, FBL11 functions to demethylate the Lys-36 residue of histone H3, FBL11 is thought to promote the ubiquitination and subsequent degradation of various phosphorylated proteins, JHDM1A (JmjC domain-containing histone demethylation protein 1A) or LILINA, KDM2A, Three isoforms of FBL11 exist due to alternative splicing events, also known as FBXL11 (F-box and leucine-rich repeat protein 11), for degradation by the proteasome after ubiquitination, immune response, is a 1, ovary and brain, signaling cascades and developmental programs by targeting proteins, such as cyclins, thereby modulating the histone code, 162 amino acid member of the F-box protein family that contains one F-box domain and localizes to the nucleus, F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CXXC-type zinc finger protein 8, CXXC8, F box / LRR repeat protein 11, F box and leucine rich repeat protein 11, F box protein FBL7, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, F-box/LRR-repeat protein 11, FBL11, FBL7, FBXL11, JHDM1A, JmjC domain-containing histone demethylation protein 1A, KDM2A_HUMAN, Lysine-specic demethylase 2A, kdm2a, [Histone-H3]-lysine-36 demethylase 1A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FBXL11 |
| Short name: |
FBXL11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FBXL11 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13606 |
| Gene: |
KDM2A |
More about : KDM2A |
| Long gene name: |
lysine demethylase 2A |
| Synonyms gene: |
FBXL11 |
| Synonyms gene name: |
F-box and leucine-rich repeat protein 11 lysine (K)-specific demethylase 2A |
| Synonyms: |
KIAA1004 FBL11 LILINA DKFZP434M1735 FBL7 FLJ00115 CXXC8 JHDM1A |
| Synonyms name: |
F-box protein FBL11 jumonji C domain-containing histone demethylase 1A |
| Locus: |
11q13, 2 |
| Discovery year: |
2000-09-27 |
| GenBank acession: |
BC047486 |
| Entrez gene record: |
22992 |
| Pubmed identfication: |
10231032 10531037 |
| RefSeq identity: |
NM_012308 |
| Classification: |
PHD finger proteins Lysine demethylases F-box and leucine rich repeat proteins Zinc fingers CXXC-type |
| Havana BLAST/BLAT: |
OTTHUMG00000167103 |