| Long name: |
ALEXA FLUOR 488 Conjugated, FBXL11 Polyclonal Antibody |
| Also known as: |
Anti-FBXL11 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FBXL11 |
| Specificity: |
This is a highly specific antibody against FBXL11 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FBXL11 |
| Gene ID Number: |
22992 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Additionally, CXXC8, Expressed ubiquitously with highest expression in testis, F-box proteins are members of a large family that regulate the cell cycle, FBL11, FBL11 functions to demethylate the Lys-36 residue of histone H3, FBL11 is thought to promote the ubiquitination and subsequent degradation of various phosphorylated proteins, JHDM1A (JmjC domain-containing histone demethylation protein 1A) or LILINA, KDM2A, Three isoforms of FBL11 exist due to alternative splicing events, also known as FBXL11 (F-box and leucine-rich repeat protein 11), for degradation by the proteasome after ubiquitination, immune response, is a 1, ovary and brain, signaling cascades and developmental programs by targeting proteins, such as cyclins, thereby modulating the histone code, 162 amino acid member of the F-box protein family that contains one F-box domain and localizes to the nucleus, F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
KIAA1004 FBL11 LILINA DKFZP434M1735 FBL7 FLJ00115 CXXC8 JHDM1A |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FBXL11 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
FBXL11 |
| Short name: |
FBXL11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, FBXL11 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13606 |
| Gene: |
KDM2A |
More about : KDM2A |
| Long gene name: |
lysine demethylase 2A |
| Synonyms gene: |
FBXL11 |
| Synonyms gene name: |
F-box and leucine-rich repeat protein 11 lysine (K)-specific demethylase 2A |
| Synonyms name: |
F-box protein FBL11 jumonji C domain-containing histone demethylase 1A |
| Locus: |
11q13, 2 |
| Discovery year: |
2000-09-27 |
| GenBank acession: |
BC047486 |
| Entrez gene record: |
22992 |
| Pubmed identfication: |
10231032 10531037 |
| RefSeq identity: |
NM_012308 |
| Classification: |
PHD finger proteins Lysine demethylases F-box and leucine rich repeat proteins Zinc fingers CXXC-type |
| Havana BLAST/BLAT: |
OTTHUMG00000167103 |