| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FBXL11 |
| Specificity: |
This antibody reacts specifically with FBXL11 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FBXL11 |
| Gene ID: |
22992 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additionally, CXXC8, Expressed ubiquitously with highest expression in testis, F-box proteins are members of a large family that regulate the cell cycle, FBL11, FBL11 functions to demethylate the Lys-36 residue of histone H3, FBL11 is thought to promote the ubiquitination and subsequent degradation of various phosphorylated proteins, JHDM1A (JmjC domain-containing histone demethylation protein 1A) or LILINA, KDM2A, Three isoforms of FBL11 exist due to alternative splicing events, also known as FBXL11 (F-box and leucine-rich repeat protein 11), for degradation by the proteasome after ubiquitination, immune response, is a 1, ovary and brain, signaling cascades and developmental programs by targeting proteins, such as cyclins, thereby modulating the histone code, 162 amino acid member of the F-box protein family that contains one F-box domain and localizes to the nucleus, F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1004 FBL11 LILINA DKFZP434M1735 FBL7 FLJ00115 CXXC8 JHDM1A |
| Also known as: |
FBXL11 Polyclonal Antibody |
| Other name: |
Anti-FBXL11 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FBXL11 |
| Short name: |
Anti-FBXL11 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FBXL11 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13606 |
| Gene: |
KDM2A |
More about : KDM2A |
| Long gene name: |
lysine demethylase 2A |
| Synonyms gene: |
FBXL11 |
| Synonyms gene name: |
F-box and leucine-rich repeat protein 11 lysine (K)-specific demethylase 2A |
| Synonyms name: |
F-box protein FBL11 jumonji C domain-containing histone demethylase 1A |
| Locus: |
11q13, 2 |
| Discovery year: |
2000-09-27 |
| GenBank acession: |
BC047486 |
| Entrez gene record: |
22992 |
| Pubmed identfication: |
10231032 10531037 |
| RefSeq identity: |
NM_012308 |
| Classification: |
PHD finger proteins Lysine demethylases F-box and leucine rich repeat proteins Zinc fingers CXXC-type |
| Havana BLAST/BLAT: |
OTTHUMG00000167103 |