| Long name: |
FITC Conjugated, SCN8A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SCN8A |
| Specificity: |
This is a highly specific antibody against SCN8A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
6, KLH conjugated synthetic peptide derived from human SCN8A/Nav1 |
| Gene ID number: |
6334 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Assuming opened or closed conformations in response to the voltage difference across the membrane, In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient, Mediates the voltage-dependent sodium ion permeability of excitable membranes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Nav1, 6 NaCh6 PN4 CerIII |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SCN8A Conjugated |
| Short name: |
FITC Conjugated, SCN8A Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SCN8A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10596 |
| Gene: |
SCN8A |
More about : SCN8A |
| Long gene name: |
sodium voltage-gated channel alpha subunit 8 |
| Synonyms gene: |
MED |
| Synonyms gene name: |
alpha polypeptide sodium channel, alpha subunit sodium channel, sodium channel, type VIII, type VIII, type VIII alpha subunit , voltage gated, voltage gated, voltage gated |
| Locus: |
12q13, 1 |
| Discovery year: |
1995-08-23 |
| GenBank acession: |
AB027567 |
| Entrez gene record: |
6334 |
| Pubmed identfication: |
7670495 9828131 16382098 |
| RefSeq identity: |
NM_014191 |
| Classification: |
Sodium voltage-gated channel alpha subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000169490 |