| Long name: |
SCN8A Primary Polyclonal Antibody |
| Also known as: |
SCN8A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SCN8A |
| Specificity: |
This is a highly specific antibody against SCN8A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
6, This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SCN8A/Nav1 |
| Gene ID number: |
6334 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Assuming opened or closed conformations in response to the voltage difference across the membrane, In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient, Mediates the voltage-dependent sodium ion permeability of excitable membranes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MED, Motor endplate disease, NaCh 6, NaCh6, Nav 1, Nbna1, PN 4, PN4, SCN8A_HUMAN, Scn8a, Sodium channel protein type 8 alpha subunit, Sodium channel protein type 8 subunit alpha, Sodium channel protein type VIII alpha subunit, Sodium channel protein type VIII subunit alpha, Sodium channel voltage gated type VIII alpha, Sodium channel voltage gated type VIII alpha polypeptide, Sodium channel voltage gated type VIII alpha subunit, Voltage gated sodium channel subunit alpha Nav1, Voltage-gated sodium channel subunit alpha Nav1, hNa6/Scn8a voltage gated sodium channel, 6, 6, 6, CerIII |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SCN8A |
| Short name: |
SCN8A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SCN8A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10596 |
| Gene: |
SCN8A |
More about : SCN8A |
| Long gene name: |
sodium voltage-gated channel alpha subunit 8 |
| Synonyms gene: |
MED |
| Synonyms gene name: |
alpha polypeptide sodium channel, alpha subunit sodium channel, sodium channel, type VIII, type VIII, type VIII alpha subunit , voltage gated, voltage gated, voltage gated |
| Synonyms: |
Nav1, 6 NaCh6 PN4 CerIII |
| Locus: |
12q13, 1 |
| Discovery year: |
1995-08-23 |
| GenBank acession: |
AB027567 |
| Entrez gene record: |
6334 |
| Pubmed identfication: |
7670495 9828131 16382098 |
| RefSeq identity: |
NM_014191 |
| Classification: |
Sodium voltage-gated channel alpha subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000169490 |