| Long name: |
Biotin Conjugated, SCN8A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SCN8A |
| Specificity: |
This is a highly specific antibody against SCN8A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
6, KLH conjugated synthetic peptide derived from human SCN8A/Nav1 |
| Gene ID number: |
6334 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Assuming opened or closed conformations in response to the voltage difference across the membrane, In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient, Mediates the voltage-dependent sodium ion permeability of excitable membranes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Nav1, 6 NaCh6 PN4 CerIII |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SCN8A Conjugated |
| Short name: |
Conjugated, SCN8A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, SCN8A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10596 |
| Gene: |
SCN8A |
More about : SCN8A |
| Long gene name: |
sodium voltage-gated channel alpha subunit 8 |
| Synonyms gene: |
MED |
| Synonyms gene name: |
alpha polypeptide sodium channel, alpha subunit sodium channel, sodium channel, type VIII, type VIII, type VIII alpha subunit , voltage gated, voltage gated, voltage gated |
| Locus: |
12q13, 1 |
| Discovery year: |
1995-08-23 |
| GenBank acession: |
AB027567 |
| Entrez gene record: |
6334 |
| Pubmed identfication: |
7670495 9828131 16382098 |
| RefSeq identity: |
NM_014191 |
| Classification: |
Sodium voltage-gated channel alpha subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000169490 |