RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody, ALEXA FLUOR 594

Catalog number:	bs-6581R-A594 Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody, ALEXA FLUOR 594
Quantity:	0.1ml
Related search:	rna polymerase ctd ser antibody antibodies transcription cleft dna crossreactivity

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Long name:	ALEXA FLUOR 594 Conjugated, RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody
Also known as:	Anti-RNA polymerase II CTD repeat YSPTSPS phospho Ser2 PAb ALEXA FLUOR 594
Category:	Conjugated Primary Antibodies
Conjugated with:	594, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	RNA polymerase II CTD repeat YSPTSPS phospho Ser2
Specificity:	This is a highly specific antibody against RNA polymerase II CTD repeat YSPTSPS phospho Ser2
Modification:	Phosphorylation
Modification Site:	Ser2
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	1600-1630/1970
Subcellular location:	Nucleus
Source:	KLH conjugated synthetic phosphopeptide derived from human RNA polymerase II RPB1 around Ser2
Gene ID Number:	6193
Swiss Prot:	P46782
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition, Acts as a RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, At the start of transcription, During transcription elongation, Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), Forms the polymerase active center together with the second largest subunit, It is composed of mobile elements that move relative to each other, Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs, Pol II is the central component of the basal RNA polymerase II transcription machinery, Pol II moves on the template as the transcript elongates, RPB1 is part of the core element with the central large cleft, a single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II, acting both as a replicate and transcriptase for the viral RNA circular genome, elongation, termination and mRNA processing, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template, which serves as a platform for assembly of factors that regulate transcription initiation, DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	590nm/617nm
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	594, ALEXA FLUOR®, Alexa Fluor
Conjugated:	Alexa conjugate 1
Gene target:	RNA polymerase II CTD repeat YSPTSPS (Ser2)
Short name:	RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 594
Alternative name:	ALEXA FLUOR 594, RNA polymerizing enzyme II CTD repeat YSPTSPS (Ser2) (Antibody to)
Alternative technique:	antibodies
Identity:	2497
Gene:	CTD | More about : CTD
Long gene name:	Coats disease
Locus:	reserved
Discovery year:	1994-01-05
Entrez gene record:	1283
Pubmed identfication:	11884883 10484772

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• #polymerase
• #ctd
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• #antibodies
• #transcription
• #cleft
• #dna
• #crossreactivity