| Long name: |
ALEXA FLUOR 647 Conjugated, RNA polymerase II CTD repeat YSPTSPS (Ser5) Antibody |
| Also known as: |
Anti-RNA polymerase II CTD repeat YSPTSPS phospho Ser5 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RNA polymerase II CTD repeat YSPTSPS phospho Ser5 |
| Specificity: |
This is a highly specific antibody against RNA polymerase II CTD repeat YSPTSPS phospho Ser5 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser5 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human RNA polymerase II CTD repeat YSPTSPS around the phosphorylation site of phospho S5 |
| Gene ID Number: |
6193 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition, Acts as a RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, At the start of transcription, During transcription elongation, Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), Forms the polymerase active center together with the second largest subunit, It is composed of mobile elements that move relative to each other, Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs, Pol II is the central component of the basal RNA polymerase II transcription machinery, Pol II moves on the template as the transcript elongates, RPB1 is part of the core element with the central large cleft, a single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II, acting both as a replicate and transcriptase for the viral RNA circular genome, elongation, termination and mRNA processing, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template, which serves as a platform for assembly of factors that regulate transcription initiation, DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the RNA polymerase II CTD repeat YSPTSPS (Ser5) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
RNA polymerase II CTD repeat YSPTSPS (Ser5) |
| Short name: |
RNA polymerase II CTD repeat YSPTSPS (Ser5) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, RNA polymerizing enzyme II CTD repeat YSPTSPS (Ser5) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2497 |
| Gene: |
CTD |
More about : CTD |
| Long gene name: |
Coats disease |
| Locus: |
reserved |
| Discovery year: |
1994-01-05 |
| Entrez gene record: |
1283 |
| Pubmed identfication: |
11884883 10484772 |