RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody

Catalog number:	bs-6581R Buy Now
Price:	516 €
Supplier:	Bioss Polyclonal Antibodies
Product name:	RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody
Quantity:	100 microliters
Related search:	rna polymerase antibody ser ysptsps antibodies transcription cleft number

More details Need more?:

Long name:	RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody
Also known as:	RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	RNA polymerase II CTD repeat YSPTSPS phospho Ser2
Specificity:	This is a highly specific antibody against RNA polymerase II CTD repeat YSPTSPS phospho Ser2
Modification(s):	Phosphorylation
Modification site(s):	Ser2
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	1600-1630/1970
Subcellular location:	Nucleus
Source:	KLH conjugated synthetic phosphopeptide derived from human RNA polymerase II RPB1 around Ser2
Gene ID number:	6193
Swiss Prot:	P46782
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition, Acts as a RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, At the start of transcription, During transcription elongation, Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), Forms the polymerase active center together with the second largest subunit, It is composed of mobile elements that move relative to each other, Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs, Pol II is the central component of the basal RNA polymerase II transcription machinery, Pol II moves on the template as the transcript elongates, RPB1 is part of the core element with the central large cleft, a single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II, acting both as a replicate and transcriptase for the viral RNA circular genome, elongation, termination and mRNA processing, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template, which serves as a platform for assembly of factors that regulate transcription initiation, DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	40S ribosomal protein S5, RPS5, S5
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	RNA polymerase II CTD repeat YSPTSPS (Ser2)
Short name:	RNA polymerase II CTD repeat YSPTSPS (Ser2) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	RNA polymerizing enzyme II CTD repeat YSPTSPS (Ser2) (Antibody to)
Alternative technique:	antibodies
Identity:	2497
Gene:	CTD | More about : CTD
Long gene name:	Coats disease
Locus:	reserved
Discovery year:	1994-01-05
Entrez gene record:	1283
Pubmed identfication:	11884883 10484772

• #rna
• #polymerase
• #antibody
• #ser
• #ysptsps
• #antibodies
• #transcription
• #cleft
• #number