| Long name: |
FITC Conjugated, SHP2 (Tyr81) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SHP2 Tyr81 |
| Specificity: |
This is a highly specific antibody against SHP2 Tyr81 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr81 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human SHP2 around the phosphorylation site of 81 |
| Gene ID number: |
3636 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A second and much more widely expressed PTP with SH2 domains, HCP and SHP), SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, SHPTP2 (also designated PTP1D and Syp), Several groups have independently identified a non transmembrane PTP, and cell migration, designated SHPTP1 (also known as PTP1C, has been identified, metabolic control, such as mitogenic activation, transcription regulation, which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain, The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
BPTP3 SH-PTP2 SHP-2 PTP2C SHP2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SHP2 (Tyr81) Conjugated |
| Short name: |
FITC Conjugated, SHP2 (Tyr81) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SHP2 (Tyr81) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9644 |
| Gene: |
PTPN11 |
More about : PTPN11 |
| Long gene name: |
non-receptor type 11 , protein tyrosine phosphatase |
| Synonyms gene: |
NS1 |
| Synonyms gene name: |
Noonan syndrome 1 |
| Locus: |
12q24, 13 |
| Discovery year: |
1993-03-03 |
| GenBank acession: |
D13540 |
| Entrez gene record: |
5781 |
| Pubmed identfication: |
7894486 1280823 |
| Classification: |
Protein tyrosine phosphatases, non-receptor type SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000134334 |
| Locus Specific Databases: |
LRG_614 |