| Long name: |
Cy7 Conjugated, SHP2 (Tyr81) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SHP2 Tyr81 |
| Specificity: |
This is a highly specific antibody against SHP2 Tyr81 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr81 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human SHP2 around the phosphorylation site of 81 |
| Gene ID number: |
3636 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A second and much more widely expressed PTP with SH2 domains, HCP and SHP), SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, SHPTP2 (also designated PTP1D and Syp), Several groups have independently identified a non transmembrane PTP, and cell migration, designated SHPTP1 (also known as PTP1C, has been identified, metabolic control, such as mitogenic activation, transcription regulation, which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain, The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
BPTP3 SH-PTP2 SHP-2 PTP2C SHP2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
SHP2 (Tyr81) Conjugated |
| Short name: |
Conjugated, SHP2 (Tyr81) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, SHP2 (Tyr81) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9644 |
| Gene: |
PTPN11 |
More about : PTPN11 |
| Long gene name: |
non-receptor type 11 , protein tyrosine phosphatase |
| Synonyms gene: |
NS1 |
| Synonyms gene name: |
Noonan syndrome 1 |
| Locus: |
12q24, 13 |
| Discovery year: |
1993-03-03 |
| GenBank acession: |
D13540 |
| Entrez gene record: |
5781 |
| Pubmed identfication: |
7894486 1280823 |
| Classification: |
Protein tyrosine phosphatases, non-receptor type SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000134334 |
| Locus Specific Databases: |
LRG_614 |