ERK5 (Ser731+Thr733) Antibody, FITC Conjugated

Catalog number:	bs-5486R-FITC Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	ERK5 (Ser731+Thr733) Antibody, FITC Conjugated
Quantity:	0.1ml
Related search:	antibody antibodies mapk gene kinase fluorescent storage

More details Need more?:

Long name:	FITC Conjugated, ERK5 (Ser731+Thr733) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Anti-FITC Antibody
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ERK5 Ser731+Thr733
Specificity:	Recognizes Ser721+Thr723 in mice and rats, This is a highly specific antibody against ERK5 Ser731+Thr733
Modification:	Phosphorylation
Modification site:	Ser731+Thr733
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	725-740/816
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human ERK5 around the phosphorylation sites of Ser731+Thr733
Gene ID number:	5598
Swiss Prot:	Q13164
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway, Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction, MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways, May be important for endothelial function and maintenance of blood vessel integrity, May have a role in muscle cell differentiation, Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression, The upstream activator of MAPK7 is the MAPK kinase MAP2K5, Upon activation, differentiation and cell survival, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C, Plays a role in various cellular processes such as proliferation
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	494nm/518nm
Synonyms:	BMK1 ERK5
Properties:	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	ERK5 (Ser731+Thr733) Conjugated
Short name:	FITC Conjugated, ERK5 (Ser731+Thr733) Antibody
Technique:	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	FITC
Alternative name:	fluorecein coupled, ERK5 (Ser731+Thr733) (Antibody to)
Alternative technique:	antibodies
Identity:	6880
Gene:	MAPK7 | More about : MAPK7
Long gene name:	mitogen-activated protein kinase 7
Synonyms gene:	PRKM7
Synonyms name:	BMK1 kinase extracellular-signal-regulated kinase 5
Locus:	17p11, 2
Discovery year:	1998-04-28
GenBank acession:	U25278
Entrez gene record:	5598
Pubmed identfication:	10072598 7759517
RefSeq identity:	NM_139033
Classification:	Mitogen-activated protein kinases
Havana BLAST/BLAT:	OTTHUMG00000059587

• #antibody
• #antibodies
• #mapk
• #gene
• #kinase
• #fluorescent
• #storage