ERK5 (Ser731+Thr733) Antibody

Catalog number:	bs-5486R Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	ERK5 (Ser731+Thr733) Antibody
Quantity:	100ul
Related search:	erk mapk antibody kinase gene bmk synonyms year

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Long name:	ERK5 (Ser731+Thr733) Primary Polyclonal Antibody
Also known as:	ERK5 (Ser731+Thr733) PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	ERK5 Ser731+Thr733
Specificity:	Recognizes Ser721+Thr723 in mice and rats, This is a highly specific antibody against ERK5 Ser731+Thr733
Modification(s):	Phosphorylation
Modification site(s):	Ser731+Thr733
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	725-740/816
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human ERK5 around the phosphorylation sites of Ser731+Thr733
Gene ID number:	5598
Swiss Prot:	Q13164
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway, Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction, MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways, May be important for endothelial function and maintenance of blood vessel integrity, May have a role in muscle cell differentiation, Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression, The upstream activator of MAPK7 is the MAPK kinase MAP2K5, Upon activation, differentiation and cell survival, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C, Plays a role in various cellular processes such as proliferation
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	BMK-1, Big MAP kinase 1, ERK-5, ERK4, ERK5, Extracellular signal-regulated kinase 5, MAP kinase 7, MAPK 7, MAPK7, Mitogen-activated protein kinase 7, PRKM7, BMK1
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	ERK5 (Ser731+Thr733)
Short name:	ERK5 (Ser731+Thr733) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	ERK5 (Ser731+Thr733) (Antibody to)
Alternative technique:	antibodies
Identity:	6880
Gene:	MAPK7 | More about : MAPK7
Long gene name:	mitogen-activated protein kinase 7
Synonyms gene:	PRKM7
Synonyms:	BMK1 ERK5
Synonyms name:	BMK1 kinase extracellular-signal-regulated kinase 5
Locus:	17p11, 2
Discovery year:	1998-04-28
GenBank acession:	U25278
Entrez gene record:	5598
Pubmed identfication:	10072598 7759517
RefSeq identity:	NM_139033
Classification:	Mitogen-activated protein kinases
Havana BLAST/BLAT:	OTTHUMG00000059587

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