ERK5 Antibody, Biotin Conjugated

Catalog number:	bs-6396R-Biotin Buy Now
Price:	587 €
Supplier:	acr
Product name:	ERK5 Antibody, Biotin Conjugated
Quantity:	0,4 ml
Related search:	antibody mapk antibodies gene kinase synonyms short

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Long name:	Biotin Conjugated, ERK5 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ERK5
Specificity:	This is a highly specific antibody against ERK5
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	75-125/816
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from human ERK5/MAPK7
Gene ID number:	5598
Swiss Prot:	Q13164
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway, Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction, MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways, May be important for endothelial function and maintenance of blood vessel integrity, May have a role in muscle cell differentiation, Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression, The upstream activator of MAPK7 is the MAPK kinase MAP2K5, Upon activation, differentiation and cell survival, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C, Plays a role in various cellular processes such as proliferation
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	BMK1 ERK5
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	ERK5 Conjugated
Short name:	Conjugated, ERK5 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, ERK5 (Antibody to)
Alternative technique:	antibodies
Identity:	6880
Gene:	MAPK7 | More about : MAPK7
Long gene name:	mitogen-activated protein kinase 7
Synonyms gene:	PRKM7
Synonyms name:	BMK1 kinase extracellular-signal-regulated kinase 5
Locus:	17p11, 2
Discovery year:	1998-04-28
GenBank acession:	U25278
Entrez gene record:	5598
Pubmed identfication:	10072598 7759517
RefSeq identity:	NM_139033
Classification:	Mitogen-activated protein kinases
Havana BLAST/BLAT:	OTTHUMG00000059587

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