ERK5 (Ser731+Thr733) Antibody, ALEXA FLUOR 488

Catalog number:	bs-5486R-A488 Buy Now
Price:	516 €
Supplier:	Bioss Polyclonal Antibodies
Product name:	ERK5 (Ser731+Thr733) Antibody, ALEXA FLUOR 488
Quantity:	100 microliters
Related search:	serthr antibody mapk gene conjugated kinase synonyms stability

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Long name:	ALEXA FLUOR 488 Conjugated, ERK5 (Ser731+Thr733) Polyclonal Antibody
Also known as:	Anti-ERK5 Ser731+Thr733 PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ERK5 Ser731+Thr733
Specificity:	This is a highly specific antibody against ERK5 Ser731+Thr733
Modification:	Phosphorylation
Modification Site:	Ser731+Thr733
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	725-740/816
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human ERK5 around the phosphorylation sites of Ser731+Thr733
Gene ID Number:	5598
Swiss Prot:	Q13164
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway, Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction, MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways, May be important for endothelial function and maintenance of blood vessel integrity, May have a role in muscle cell differentiation, Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression, The upstream activator of MAPK7 is the MAPK kinase MAP2K5, Upon activation, differentiation and cell survival, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C, Plays a role in various cellular processes such as proliferation
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Synonyms:	BMK1 ERK5
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ERK5 (Ser731+Thr733) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	ERK5 (Ser731+Thr733)
Short name:	ERK5 (Ser731+Thr733) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, ERK5 (Ser731+Thr733) (Antibody to)
Alternative technique:	antibodies
Identity:	6880
Gene:	MAPK7 | More about : MAPK7
Long gene name:	mitogen-activated protein kinase 7
Synonyms gene:	PRKM7
Synonyms name:	BMK1 kinase extracellular-signal-regulated kinase 5
Locus:	17p11, 2
Discovery year:	1998-04-28
GenBank acession:	U25278
Entrez gene record:	5598
Pubmed identfication:	10072598 7759517
RefSeq identity:	NM_139033
Classification:	Mitogen-activated protein kinases
Havana BLAST/BLAT:	OTTHUMG00000059587

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