| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ERK5 |
| Specificity: |
This antibody reacts specifically with ERK5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ERK5/MAPK7 |
| Gene ID: |
6300 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported, In response to extracelluar signals, It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, Jul 2008], MAP kinases act as an integration point for multiple biochemical signals, This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5), [provided by RefSeq, and G protein-coupled receptors, and activating different transcription factors, and are involved in a wide variety of cellular processes such as proliferation, differentiation, this kinase translocates to cell nucleus, transcription regulation and development, where it regulates gene expression by phosphorylating, The protein encoded by this gene is a member of the MAP kinase family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BMK1 ERK5 |
| Also known as: |
ERK5 Polyclonal Antibody |
| Other name: |
Anti-ERK5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ERK5 |
| Short name: |
Anti-ERK5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ERK5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6880 |
| Gene: |
MAPK7 |
More about : MAPK7 |
| Long gene name: |
mitogen-activated protein kinase 7 |
| Synonyms gene: |
PRKM7 |
| Synonyms name: |
BMK1 kinase extracellular-signal-regulated kinase 5 |
| Locus: |
17p11, 2 |
| Discovery year: |
1998-04-28 |
| GenBank acession: |
U25278 |
| Entrez gene record: |
5598 |
| Pubmed identfication: |
10072598 7759517 |
| RefSeq identity: |
NM_139033 |
| Classification: |
Mitogen-activated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000059587 |