| Long name: |
Biotin Conjugated, MLCK Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MLCK |
| Specificity: |
This is a highly specific antibody against MLCK |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
700-750/1914 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human MLCK |
| Gene ID number: |
4638 |
| Swiss Prot: |
Q15746 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A pseudogene is located on the p arm of chromosome 3, Additional variants have been identified but lack full length transcripts, Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin, In addition, Jul 2008], This gene encodes both smooth muscle and nonmuscle isoforms, This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity, [provided by RefSeq, a muscle member of the immunoglobulin gene superfamily, a small protein identical in sequence to the C-terminus of myosin light chain kinase, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme, it encodes telokin, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments, using a separate promoter in an intron in the 3' region, This gene |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
caMLCK MLCK |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MLCK Conjugated |
| Short name: |
Conjugated, MLCK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, MLCK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29826 |
| Gene: |
MYLK3 |
More about : MYLK3 |
| Long gene name: |
myosin light chain kinase 3 |
| Synonyms name: |
MLC kinase |
| Locus: |
16q11, 2 |
| Discovery year: |
2008-01-23 |
| GenBank acession: |
AJ247087 |
| Entrez gene record: |
91807 |
| Pubmed identfication: |
17885681 |
| RefSeq identity: |
NM_182493 |
| Havana BLAST/BLAT: |
OTTHUMG00000132543 |