| Long name: |
ALEXA FLUOR 647 Conjugated, MLCK Polyclonal Antibody |
| Also known as: |
Anti-MLCK PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MLCK |
| Specificity: |
This is a highly specific antibody against MLCK |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
700-750/1914 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MLCK |
| Gene ID Number: |
4638 |
| Swiss Prot: |
Q15746 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A pseudogene is located on the p arm of chromosome 3, Additional variants have been identified but lack full length transcripts, Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin, In addition, Jul 2008], This gene encodes both smooth muscle and nonmuscle isoforms, This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity, [provided by RefSeq, a muscle member of the immunoglobulin gene superfamily, a small protein identical in sequence to the C-terminus of myosin light chain kinase, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme, it encodes telokin, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments, using a separate promoter in an intron in the 3' region, This gene |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
caMLCK MLCK |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MLCK Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MLCK |
| Short name: |
MLCK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, MLCK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29826 |
| Gene: |
MYLK3 |
More about : MYLK3 |
| Long gene name: |
myosin light chain kinase 3 |
| Synonyms name: |
MLC kinase |
| Locus: |
16q11, 2 |
| Discovery year: |
2008-01-23 |
| GenBank acession: |
AJ247087 |
| Entrez gene record: |
91807 |
| Pubmed identfication: |
17885681 |
| RefSeq identity: |
NM_182493 |
| Havana BLAST/BLAT: |
OTTHUMG00000132543 |